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Reagents for Untangling AD Mechanism
Alzheimer's disease (AD) is the most common form of dementia for people over 65 years of age. AD is associated with formation of amyloid plaques and neurofibrillary tangles in the brain. Numerous cellular pathways are investigated for early diagnosis, treatment and symptoms management. Abbiotec offers over 200 antibodies, peptides and proteins for studying the detection, progression, treatment, and cell signaling events associated with AD. Browse our catalog for rabbit, mouse and rat antibodiesthat are developed for ELISA, western blot, IHC and immunofluorescence applications.
Download our Alzheimer's Disease Product Brochure here.
Amyloid Plaques
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Alpha-Synuclein, APP, Beta-Amyloid [1-42], [1-40], [1-16], [1-28], ERAB, Fe65
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Biomarkers
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ApoE, Aromatase, ChAT, CHRM1, GFAP, NMDAR, NTP, PSD-95
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Growth Factors &
Receptors
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NGF, NGFR, TGF-beta 1/2/3, TGF-beta Receptors I/II, TrkA/B/C, Tyro 3, VEGF, VEGFR1/2/3
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Inflammation
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AGE, CD Markers, G-CSF, Interleukins, M-CSF, TNF-alpha, TNFR, RAGE
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Neurofibrillary Tangles
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NF H/L/M, Tau, phospho-Tau, Tubulins alpha/beta/gamma
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Neuroprotection
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ADNP, BDNF, Col VI, Galanin, Gelsolin, HSP25, 27, 40, 60, 70, 90 Substance P, Substance P Receptor
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Oxidation
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HO-1, NOS-1/2/3, SOD 1/2
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Phosphorylation
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Cdk5, GSK3b, PKN2, PP1, PP2A/B, PTEN
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Proteases
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BACE, Calpain 1, 2, 3, 5, 6, 9, 10, Caspase 1, 3, 6, 8, 9, 10, Notch1/2, Presenilin-1
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Signaling
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AKT-1/2/3, Beta-catenin, phospho-AKT1, PI3KCA, PI3KC3, SMAD1/2/4, STAT3, TRADD, phospho-Synapsin 1/2/3, Synaptotagmin
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Peptides
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Autocamtide-2, Beta-Amyloid [1-42], [1-40], [25-35], Calcineurin Autoinhibitory, Calcineurin Substrate, Cathepsin L Substance, CREBtide, Kemptide, Protein Kinase C [19-35], Ser25 PKC [19-31], Substance P, Tyrosine Proteine Kinase Substrate
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| Proteins |
NGF-beta, VEGF, VEGFR |
Contact our Customer Service Dept for comprehensive listing, availability, and new products to be released.
SPECIAL OFFER - Until March 31, 2016 – Save 10% on Alzheimer's Disease Antibodies, Proteins and Peptides. Use promo code ENEWS0216 at time of order. Terms and conditions apply.
LATEST PRODUCT CITATIONS - For a complete list of product citations, refer to the citation webpage.
Cat. No. 250589 CD31 (N-term) Antibody for IHC in mouse tumor tissues
Kim MN. et al. 2015. Cancer Chemother Pharmacol. PMID 26037205. Efficacy of perifosine alone and in combination with sorafenib in an HrasG12V plus shp53 transgenic mouse model of hepatocellular carcinoma.
Cat. No. 250716 IL-1 beta Antibody for IHC in dog kidney tissues
Esch KJ. et al. 2015. Am J Pathol. PMID 26079813. Activation of autophagy and nucleotide-binding domain leucine-rich repeat-containing-like receptor family, pyrin domain-containing 3 inflammasome during Leishmania infantum-associated glomerulonephritis.
Cat. No. 250752 MMP-2 Antibody for WB in human osteosarcoma MG-63 cells
Zhu J. et al. 2015. Mol Med Rep. PMID 25634369. Activin A regulates proliferation, invasion and migration in osteosarcoma cells.
Cat. No. 250920 Beta-Actin Antibody for WB in human osteosarcoma MG-63 cells
Meng Q. et al. 2014. Tumour Biol. PMID 25168370. HMGB1 promotes cellular proliferation and invasion, suppresses cellular apoptosis in osteosarcoma.
Cat. No. 251361 CD144 Antibody for WB in adipose-derived stem cells
McDaniel J. et al. 2014. J Surg Res. PMID 24969547. Characterization and multilineage potential of cells derived from microvascular fragments.
ABBIOTEC is a biotech company founded in 2007 in San Diego, California, a renowned world-class Life Sciences cluster that hosts more than 1,500 research labs and biotech companies. We are focused on developing, producing and commercializing next generation antibodies and unique reagents for the Life Sciences research community including the diagnostic and pharmaceutical markets.
ABBIOTEC offers years of expertise making antibodies and assay kits for catalog products to the scientific and biotech community. With our USDA-certified animal facility, we offer polyclonal antibody production in small and large animals (rabbits, goats, llama) as well as monoclonal antibody production (mice and rats). Because peptide chemistry is an essential tool to biology, we offer custom peptide synthesis services for research-grade peptides.
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