AKR1C3 Antibody；醛固酮还原酶家族1成员C3抗体-ABBIOTEC

克隆类型 ：

Rabbit Polyclonal Antibody

亚 型 ：

Rabbit Ig

免 疫 原 ：

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human AKR1C3.

产品描述 ：

Aldo-keto reductase family 1 member C3 (AKR1C3) catalyzes the conversion of aldehydes and ketones to alcohols. AKR1C3 catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. AKR1C3 functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. AKR1C3 can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. AKR1C3 preferentially transforms androstenedione (4-dione) to testosterone. AKR1C3 is strongly inhibited by nonsteroidal anti-inflammatory drugs (NSAID) including flufenamic acid and indomethacin. AKR1C3 is also inhibited by the flavinoid rutin, and by selective serotonin inhibitors (SSRIs).

适用物种 ：

H

应用范围 ：

E, WB, IF

应用说明 ：

E: 1:10,000-1:30,000; WB: 1:100-1:1,000; IF: 1:50-1:200

别 名 ：

Aldo-keto reductase family 1 member C3; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; 3-alpha-hydroxysteroid dehydrogenase type 2; 3-alpha-HSD type 2; 3-alpha-HSD type II, brain; Testosterone 17-beta-dehydrogenase 5; 17-beta-hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; Prostaglandin F synthase; PGFS; Indanol dehydrogenase; Dihydrodiol dehydrogenase type I; Dihydrodiol dehydrogenase 3; DD-3; DD3; Chlordecone reductase homolog HAKRb; HA1753; AKR1C3; DDH1; HSD17B5; KIA0119; PGFS

形 态 ：

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

保存条件 ：

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

产品链接 ： http://www.abbiotec.com/antibodies/akr1c3-antibody
实验图片 ：